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Specific T-cell subsets have a role in anti-viral immunity and pathogenesis but not viral dynamics or onwards vector transmission of an important livestock arbovirus

Introduction: Bluetongue virus (BTV) is an arthropod-borne Orbivirus that is almost solely transmitted by Culicoides biting midges and causes a globally important haemorrhagic disease, bluetongue (BT), in susceptible ruminants. Infection with BTV is characterised by…

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Specific T-cell subsets have a role in anti-viral immunity and pathogenesis but not viral dynamics or onwards vector transmission of an important livestock arbovirus

Introduction: Bluetongue virus (BTV) is an arthropod-borne Orbivirus that is almost solely transmitted by Culicoides biting midges and causes a globally important haemorrhagic disease, bluetongue (BT), in susceptible ruminants. Infection with BTV is characterised by…

default publication image

Specific T-cell subsets have a role in anti-viral immunity and pathogenesis but not viral dynamics or onwards vector transmission of an important livestock arbovirus

Introduction: Bluetongue virus (BTV) is an arthropod-borne Orbivirus that is almost solely transmitted by Culicoides biting midges and causes a globally important haemorrhagic disease, bluetongue (BT), in susceptible ruminants. Infection with BTV is characterised by…

default publication image

Specific T-cell subsets have a role in anti-viral immunity and pathogenesis but not viral dynamics or onwards vector transmission of an important livestock arbovirus

Introduction: Bluetongue virus (BTV) is an arthropod-borne Orbivirus that is almost solely transmitted by Culicoides biting midges and causes a globally important haemorrhagic disease, bluetongue (BT), in susceptible ruminants. Infection with BTV is characterised by…

Two very young Rhode Island Red chicks

Avian bronchitis vaccine replicates in cell culture

Researchers at The Pirbright Institute have found it is possible to generate novel vaccines for avian bronchitis that are capable of replicating in cell culture. Writing in the journal PLOS One, the team outline how a virus generated using reverse genetics was found to offer…

Group of five people from Pirbright in a line smiling in front of a large white poster. One is holding a certificate.

Pirbright celebrates Athena Swan Silver Award

The quest for gender equality at The Pirbright Institute has been recognised through an Athena Swan Silver Award. The Athena Swan Charter is a framework used across the globe to support and transform gender equality within higher education (HE) and research. The five-year…

A person in a fluorescent orange jacket pointing at electrical parts on the left with two people on the right in jackets smiling

Pirbright drives energy efficiencies

The Pirbright Institute is cutting fossil fuel energy use and costs across its Surrey campus in 2024. The Institute analysed the energy efficiency of its buildings and infrastructure in 2022-23 to develop a site-wide energy plan that drives down gas and electricity…

BBSRC National Vaccinology Centre: The Jenner Building

Pirbright welcomes new BBSRC Executive Chair

The Secretary of State for Science, Innovation and Technology, Michelle Donelan, has appointed Professor Anne Ferguson-Smith as the new Executive Chair of the Biotechnology and Biological Sciences Research Council (BBSRC). Professor Ferguson-Smith is a highly respected…

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The Identification of Host Proteins That Interact with Non-Structural Proteins-1α and -1β of Porcine Reproductive and Respiratory Syndrome Virus-1

Porcine reproductive and respiratory syndrome viruses (PRRSV-1 and -2) are the causative agents of one of the most important infectious diseases affecting the global pig industry. Previous studies, largely focused on PRRSV-2, have shown that non-structural protein-1α (NSP1α)…

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A Qualitative Risk Assessment for Bluetongue Disease and African Horse Sickness: The Risk of Entry and Exposure at a UK Zoo

Bluetongue virus (BTV) and African horse sickness virus (AHSV) cause economically important diseases that are currently exotic to the United Kingdom (UK), but have significant potential for introduction and onward transmission. Given the susceptibility of animals kept in zoo…