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African swine fever virus NAM P1/95 is a mixture of genotype I and genotype VIII viruses

African swine fever virus causes a lethal hemorrhagic disease of domestic pigs. The NAM P1/1995 isolate was originally described as B646L genotype XVIII; however, full genome sequencing revealed that this assignment was incorrect.

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DEFEND celebrates five years of success

A global scientific consortium which set out to control two major livestock virus epidemics in Europe is celebrating five years of research findings. Coordinated and led by The Pirbright Institute, and funded through the European Union’s Horizon 2020 innovation and research…

Advancing African swine fever virus (ASFV) vaccines

In an effort to combat the devastating impact of African swine fever (ASF) on global food security, Pirbright researchers have secured funding from the Medical Research Council to assess the cross-protection potential of modified live vaccines (MLV) against diverse ASF virus…

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Full genome sequence analysis of African swine fever virus isolates from Cameroon

African swine fever (ASF) is a devastating disease of domestic pigs that has spread across the globe since its introduction into Georgia in 2007. The etiological agent is a large double-stranded DNA virus with a genome of 170 to 180 kb in length depending on the isolate…

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Full genome sequence analysis of African swine fever virus isolates from Cameroon

African swine fever (ASF) is a devastating disease of domestic pigs that has spread across the globe since its introduction into Georgia in 2007. The etiological agent is a large double-stranded DNA virus with a genome of 170 to 180 kb in length depending on the isolate…

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Paving the way for rapid detection of vector-borne viruses

Vector-borne viruses pose a significant global health threat, particularly in low- and middle-income tropical countries. Pirbright researchers and their collaborators from the London School of Hygiene and Tropical Medicine have secured a grant from the Medical Research…

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A novel optimized pre-embedding antibody-labelling correlative light electron microscopy technique

In the intricate environment of a cell, many studies seek to discover the location of specific events or objects of interest. Advances in microscopy in recent years have allowed for high detail views of specific areas of cells of interest using correlative light electron…

nipah virus

New collaboration to find vaccine protection for the 'known unknown'

A new collaboration between the The Pirbright Institute and the UK Health Security Agency (UKHSA) has been initiated to support the development of vaccines against a group of lethal viruses. Researchers will address the threat of outbreaks caused by previously unknown or…

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The transcriptomic insight into the differential susceptibility of African Swine Fever in inbred pigs

African swine fever (ASF) is a global threat to animal health and food security. ASF is typically controlled by strict biosecurity, rapid diagnosis, and culling of affected herds. Much progress has been made in developing modified live virus vaccines against ASF. There is…