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Success of new course in Argentina may help Institute build more links with South America

The success of a new porcine and bovine immunology course, run by Dr Maria Montoya, (in collaboration with Dr. Patricia Zamorano and Dr. Claudia Mongini from the Institute of Virology at INTA in Buenos Aires), could pave the way for The Pirbright Institute to significantly…

Pirbright scientists lead the way in developing an effective vaccine against deadly horse virus

Scientists at The Pirbright Institute are confident they have identified a safe and effective vaccination strategy for African horse sickness virus (AHSV) – the battle is now to build a business case persuasive enough to encourage a manufacturer to develop it and finally…

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Evaluation of risk factors for peste des petits ruminants virus in sheep and goats at the wildlife-livestock interface in Punjab Province, Pakistan

Peste des petits ruminants virus (PPRV) is causing infectious disease with high morbidity and mortality rate in domestic and wild small ruminants of Pakistan with valuable economical losses. The present study was carried out to investigate risk factors of PPRV in domestic…

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Lumpy skin disease: a direct threat to Europe

Lumpy skin disease (LSD) is a transboundary, systemic, viral disease of cattle that has traditionally been found in southern Africa. It has steadily expanded its geographical boundaries and in the past five years moved very efficiently through the Middle East and into…

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Genomics and outbreaks: foot-and-mouth disease.

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Genome sequencing of foot-and-mouth disease virus type O isolate GRE/23/94

The complete genome of a foot-and-mouth disease type O virus originating from an epidemic in Greece in 1994 is reported. This virus belongs to the Middle East-South Asia topotype.

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Extensive coronavirus-induced membrane rearrangements are not a determinant of pathogenicity

Positive-strand RNA (+RNA) viruses rearrange cellular membranes during replication, possibly in order to concentrate and arrange viral replication machinery for efficient viral RNA synthesis. Our previous work showed that in addition to the conserved coronavirus double…

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Extensive coronavirus-induced membrane rearrangements are not a determinant of pathogenicity

Positive-strand RNA (+RNA) viruses rearrange cellular membranes during replication, possibly in order to concentrate and arrange viral replication machinery for efficient viral RNA synthesis. Our previous work showed that in addition to the conserved coronavirus double…

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Evaluation of the in vitro expression of ATP binding-cassette (ABC) proteins in an Ixodes ricinus cell line exposed to ivermectin

Ticks are among the most important vectors of pathogens causing human and animal disease. Acaricides are used to control tick infestation, although there are increasing reports of resistance. Recently, over-expression of ATP-binding cassette (ABC) transporter proteins (P…

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Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2014)

Changes to virus taxonomy approved by a vote of all ICTV members in February-March 2014 are reported.