Search | The Pirbright Institute

Filters

default publication image

Designing a Multiplex PCR-xMAP Assay for the Detection and Differentiation of African Horse Sickness Virus, Serotypes 1-9

African horse sickness is a severe and often fatal disease affecting all species of equids. The aetiological agent, African horse sickness virus (AHSV), can be differentiated into nine serotypes. The identification of AHSV serotypes is vital for disease management, as this…

Photo of the front exterior of Pirbright's Jenner building. There are eight stone pillars. Blue sky with fluffy white clouds are see

Homepage

We are a world-leading centre of excellence in the research and surveillance of viral diseases of livestock and viruses that spread from animals to humans.

Scientist in white lab coat and blue gloves inserting hand into insect net

Insectary

Rearing and studying insect vectors of viral diseases, supporting critical research on disease transmission, vector behavior, and control for both livestock and human health.

Cows in a Bangladesh market

Host Responses to Viral Infection

Understanding how hosts respond to viruses to inform new control measures and improve vaccine protection.

Virus Life Cycles at Multiple Scales

Understanding how viruses replicate and spread.

default publication image

Evaluation of the immunogenicity of an mRNA vectored Nipah virus vaccine candidate in pigs

Nipah virus (NiV) poses a significant threat to human and livestock populations across South and Southeast Asia. Vaccines are required to reduce the risk and impact of spillover infection events. Pigs can act as an intermediate amplifying host for NiV and, separately…

default publication image

An updated framework for SARS-CoV-2 variants reflects the unpredictability of viral evolution

Throughout the COVID-19 pandemic, SARS-CoV-2 variants have been designated as variants of concern (VOCs) and variants of interest (VOIs) on the basis of their potential to replace previously circulating variants and cause new waves of increased transmission globally; such…

nipah virus

Consortium in quest for ‘single shot’ bivalent Nipah virus vaccine

An international consortium of scientists and commercial partners is aiming to develop a vaccine and companion diagnostic test for Nipah virus (NiV). The newly emerging zoonotic disease infects pigs and can spread to people. Carried by fruit bats, it can cause human…

Pioneering partnership to improve swine health

The Pirbright Institute is partnering with researchers at The Vaccine Group (TVG) in Plymouth on a new project that sets out to control African swine fever (ASF). Pirbright researchers are collaborating with TVG to accelerate the development of safe and effective vaccines…

default publication image

MAIT cell-MR1 reactivity is highly conserved across multiple divergent species

Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells that recognize small molecule metabolites presented by MHC-I related protein 1 (MR1), via an αβ T cell receptor (TCR). MAIT TCRs feature an essentially invariant TCR α-chain, which is highly…