Search | The Pirbright Institute

Filters

Plowright and Jenner building at Pirbright

Calibration basics: eLearning

Learn the background of calibration and use of SI units.

default publication image

Imd pathway-specific immune assays reveal NF-κB stimulation by viral RNA PAMPs in Aedes aegypti Aag2 cells

Background The mosquito Aedes aegypti is a major vector for the arthropod-borne viruses (arboviruses) chikungunya, dengue, yellow fever and Zika viruses. Vector immune responses pose a major barrier to arboviral transmission, and transgenic insects with altered immunity have…

default publication image

Re-evaluating the mosquito RNAi pathway’s influence on arbovirus transmission

With new RNA interference (RNAi) pathway-deficient mosquitoes, Merkling et al. invite a shift in our view of this pathway’s role in regulating arthropod-borne virus (arbovirus) transmission. While loss of RNAi function enhanced early viral replication, little impact on…

default publication image

Metabolomics analysis of CEF cells infected with avian leukosis virus subgroup J based on UHPLC-QE-MS

Avian leukosis virus subgroup J (ALV-J) is a retrovirus that can cause immunosuppression and tumors in chicken. However, relative pathogenesis is still not clear. At present, metabolomics has shown great potential in the screening of tumor metabolic markers, prognostic…

default publication image

Long-term trial of protection provided by adenovirus-vectored vaccine expressing the PPRV H protein

A recombinant, replication-defective, adenovirus-vectored vaccine expressing the H surface glycoprotein of peste des petits ruminants virus (PPRV) has previously been shown to protect goats from challenge with wild-type PPRV at up to 4 months post vaccination. Here, we…

Flock of chickens

Bird flu in cows – Pirbright scientist helps to show pasteurisation inactivates influenza viruses

A study has shown how pasteurisation temperatures, if applied for industry standard times, effectively inactivate H5N1 flu viruses in cows’ milk and render it safe to consume. The research, a collaboration between the MRC-University of Glasgow Centre for Virus Research, the…

Scientist in white lab coat and purple gloves about to look down a microscope. Behind the microscope is a computer screen showing the cells in the microscope.

Cell culture

Providing primary and secondary cell lines, mycoplasma testing, and expansion services, supporting research at the Institute.

Three people stood discussing

Research collaborations

Partner with us to access our unique facilities and turn collaborative research into impactful solutions for preventing and controlling viral diseases.

Bryan Charleston and Zheng Haixue at a purple table holding a pen with papers in front of them

Pirbright signs MoU with China’s agricultural research institute

The Pirbright Institute has signed a Memorandum of Understanding with the Chinese Academy of Agricultural Sciences (CAAS). The agreement builds on existing collaborations between Pirbright and China’s national agricultural research institutes and universities. Established in…

Bryan Charleston and Zheng Haixue at a purple table holding a pen with papers in front of them

Pirbright signs MoU with China’s agricultural research institute

The Pirbright Institute has signed a Memorandum of Understanding with the Chinese Academy of Agricultural Sciences (CAAS). The agreement builds on existing collaborations between Pirbright and China’s national agricultural research institutes and universities. Established in…