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Outbreak of peste des petits ruminants among critically endangered mongolian saiga and other wild ungulates, Mongolia, 2016-2017

The 2016-2017 introduction of peste des petits ruminants virus (PPRV) into livestock in Mongolia was followed by mass mortality of the critically endangered Mongolian saiga antelope and other rare wild ungulates. To assess the nature and population effects of this outbreak…

Recruiting of 10 new IAH Research Fellows is underway

The Institute is well advanced in the process of appointing holders to 10 new Research Fellowships. These are aimed at enabling outstanding early-stage scientists to develop their own research programme, within the remit of the Institute. The Fellowships, which will be…

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Pathophysiology of concussive non-penetrative captive bolt stunning of turkeys

The non-penetrative captive bolt (NPCB) has been proposed as a more humane and practical alternative to constant voltage electrical stunning for small-scale seasonal turkey producers. This study evaluated the effectiveness of the CASH ® Small Animal Tool (SAT) (formerly…

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Elucidating cryptic dynamics of Theileria communities in African buffalo using a high-throughput sequencing informatics approach

Increasing access to next-generation sequencing (NGS) technologies is revolutionizing the life sciences. In disease ecology, NGS-based methods have the potential to provide higher-resolution data on communities of parasites found in individual hosts as well as host…

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The relationship between the presence of antibodies and direct detection of Toxoplasma gondii in slaughtered calves and cattle in four European countries

In cattle, antibodies to Toxoplasma gondii infection are frequently detected, but evidence for the presence of T. gondii tissue cysts in cattle is limited. To study the concordance between the presence of anti- T. gondii IgG and viable tissue cysts of T. gondii in cattle…

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Transboundary movements of foot-and-mouth disease from India to Sri Lanka: A common pattern is shared by serotypes O and C

Foot-and-mouth disease (FMD) affects the livestock industry in a transboundary manner. It is essential to understand the FMD phylodynamics to assist in the disease-eradication. FMD critically affects the Sri Lankan cattle industry causing substantial economic losses. Even…

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In vitro interactions of chicken programmed cell death 1 (PD-1) and PD-1 ligand-1 1 (PD-L1)

In the present study, we determined the in vitro characteristics and binding interactions of chicken PD-1 (chPD-1) and PD-L1 (chPD-L1) and developed a panel of specific monoclonal antibodies against the two proteins. ChPD-1 and chPD-L1 sequence identities and similarities…

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Risks and challenges of arboviral diseases in Sudan: the urgent need for actions

The risk of emergence and/or re-emergence of arthropod-borne viral (arboviral) infections is rapidly growing worldwide, particularly in Africa. The burden of arboviral infections and diseases is not well scrutinized because of the inefficient surveillance systems in endemic…

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Utilising milk from pooling facilities as a novel approach for foot-and-mouth disease surveillance

This study investigated the potential of pooled milk as an alternative sample type for foot-and-mouth disease (FMD) surveillance. Real-time RT-PCR (rRT-PCR) results of pooled milk samples collected weekly from five pooling facilities in Nakuru County, Kenya, were compared…

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Cross-protection induced by a A/MAY/97 emergency vaccine against intra-serotype heterologous challenge with a foot-and-mouth disease virus from the A/ASIA/G-VII lineage

Since 2015, outbreaks of foot-and-mouth disease (FMD) in the Middle East have been caused by a new emerging viral lineage, A/ASIA/G-VII. Invitro vaccine matching data indicated that this virus poorly matched (low r 1-value) with vaccines that were being used in the region as…