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Viral emergence in marine mammals in the North Pacific may be linked to Arctic sea ice reduction

Climate change-driven alterations in Arctic environments can influence habitat availability, species distributions and interactions, and the breeding, foraging, and health of marine mammals. Phocine distemper virus (PDV), which has caused extensive mortality in Atlantic…

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Detection of ALV p27 in cloacal swabs and virus isolation medium by sELISA

Avian leukosis (AL), which is caused by avian leukosis virus (ALV), has led to substantial economic losses in the poultry industry. The kit used to detect all ALV-positive chickens in breeder flocks is very important for efficiently controlling AL. However, a new emerging…

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CRISPR/Cas9 gene editing in the West Nile Virus vector, Culex quinquefasciatus Say

Culex quinquefasciatus Say is an opportunistic blood feeder with a wide geographic distribution which is also a major vector for a range of diseases of both animals and humans. CRISPR/Cas technologies have been applied to a wide variety of organisms for both applied and…

Pirbright scientist becomes a Visiting Professor of the Nelson Mandela African Institute of Science and Technology

Dr John Anderson MBE of the BBSRC’s Institute for Animal Health at Pirbright has this month (September) been made a Visiting Professor of the Nelson Mandela African Institute of Science and Technology ( NM-AIST ). This is in recognition of his longstanding involvement in the…

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Morbilliviruses: Entry, Exit and Everything In-Between

Morbilliviruses are important pathogens, to the point that they have shaped the history of human and animal health.

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Glutaminolysis and glycolysis are essential for optimal replication of Marek's disease virus

Viruses may hijack glycolysis, glutaminolysis or fatty acid β-oxidation of host cells to provide energy and macromolecules required for efficient viral replication. Marek's disease virus (MDV) causes a deadly lymphoproliferative disease in chickens and modulates metabolism…

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Application of HDR-CRISPR/Cas9 and erythrocyte binding for rapid generation of recombinant turkey herpesvirus-vectored avian influenza virus vaccines

Avian influenza viruses (AIVs) are highly contagious and have caused huge economical loss to the poultry industry. AIV vaccines remain one of the most effective methods of controlling this disease. Turkey herpesvirus (HVT) is a commonly used live attenuated vaccine against…

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African swine fever epidemiology and control

African swine fever is a devastating disease that can result in death in almost all infected pigs. The continuing spread of African swine fever from Africa to Europe and recently to the high-pig production countries of China and others in Southeast Asia threatens global pork…

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Genetic diversity and population structure of Culex modestus across Europe: does recent appearance in the United Kingdom reveal a tendency for geographical spread?

In mainland Europe, the mosquito species Culex modestus Ficalbi (1890) is a bridge vector for West Nile virus (WNV) from its natural bird-mosquito cycle to mammals. The present study assessed the genetic diversity of Cx. modestus, as well as related Culex species, using the…

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An Illumina approach to MHC typing of Atlantic salmon

The IPD-MHC Database represents the official repository for non-human major histocompatibility complex (MHC) sequences, overseen and supported by the Comparative MHC Nomenclature Committee, providing access to curated MHC data and associated analysis tools. IPD-MHC gathers…