Search | The Pirbright Institute

Filters

Cattle and goats in Tanzania

Host defence genes may contribute to peste des petits ruminants susceptibility

Differences in the host immune response may explain why cattle are less susceptible to peste des petits ruminants (PPR) than goats, according to a collaborative research effort by scientists at The Pirbright Institute and the Tamil Nadu Veterinary and Animal Sciences…

default publication image

Exploring virus-host interactions through combined proteomic approaches identifies BANF1 as a new essential factor for African Swine Fever Virus

African swine fever virus (ASFV) causes a lethal disease in pigs and represents a significant threat to the global pork industry due to the lack of effective vaccines or treatments. Despite intensive research, many ASFV proteins remain uncharacterized. This study aimed to…

default publication image

Meeting Report on an Integrated Research Agenda for Mosquito-Borne Arboviruses

The emergence and re-emergence of mosquito-borne arbovirus (MBV) diseases pose a rapidly expanding global health threat fueled by the convergence of multiple ecologic, economic, and social factors, including climate change, land use, poverty, deficiencies of water storage…

IBDV infected cell (red), tubulin (green) and the nucleus (blue)

Pirbright scientists show how infectious bursal disease viruses may swap genetic material during infection

Live cell imaging has been used by researchers at The Pirbright Institute to reveal new information about how different strains of infectious bursal disease virus (IBDV) might swap genetic material, a process that could lead to new strains with the potential for causing more…

default publication image

The First African Swine Fever Viruses Detected in Wild Boar in Hong Kong, 2021-2023

This study represents the first report on the detection and whole-genome sequencing of African swine fever (ASF) viruses in wild boar in Hong Kong in 2021-2023. Wild boar samples collected via an ASF surveillance program by the Agriculture, Fisheries, and Conservation…

default publication image

Immunogenicity of Matrix Protein 2 Ectodomain (M2e) Displayed on Nodavirus-like Particles as Avian Influenza Vaccine for Poultry

Avian influenza is an economically significant disease affecting poultry worldwide and is caused by influenza A viruses that can range from low to highly pathogenic strains. These viruses primarily target the respiratory, digestive, and nervous systems of birds, leading to…

Bluetongue virus (BTV) cores

Pirbright determines bluetongue strain and origin in 2016 Cyprus outbreak

Scientists at The Pirbright Institute have used genetic analysis and wind modelling to show that the 2016 bluetongue outbreak in Cyprus was caused by bluetongue virus serotype 8 (BTV-8). The virus most likely crossed over to Cyprus in midges blown from the coastal regions of…

default publication image

Pathophysiology of penetrating captive-bolt stunning of horses

There has been limited research into the effectiveness of penetrating captive bolt (PCB) for stunning horses (Equus caballus) at slaughter. This study observed 100 horses at a commercial abattoir in Mexico, stunned using pneumatic PCB. Animals were assessed at the time of…

default publication image

Harnessing the highly adaptable barnase-barstar system for genetic biocontrol of Aedes aegypti

Toxin-antidote pairs can be used in gene drive systems, providing powerful means to modify mosquito populations. Here we use the toxin-antidote pair, barnase and barstar, originally identified in Bacillus amyloliquefaciens, due to their high binding affinity, small size and…

Scientists working on pig and poultry diseases visit Pirbright

On 15 January 2020 The Pirbright Institute hosted Newton Fund Swine and Poultry Research Initiative delegates from the UK, China, Thailand and the Philippines. The projects funded through the initiative have been underway for almost two years and the meeting served as part…