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News from February 2021

Pirbright reports first case of foot-and-mouth disease virus in dogs after eating infected meat

Posted: 22 February, 2021
Image shows dog heart tissue infected with foot-and-mouth disease virus (FMDV). Green and red show FMDV proteins, blue shows cell nuclei.

A case report filed by scientists at The Pirbright Institute details the first instance of naturally acquired foot-and-mouth disease virus (FMDV) infection in dogs. In this highly unusual case reported in BMC Veterinary Research, FMDV was identified in a sample of heart tissue received by Pirbright’s diagnostic laboratory, the World Reference Laboratory for Foot-and-Mouth Disease  (WRLFMD).

Stunning images allow Pirbright scientists to unpick the secrets of African swine fever viral replication

Posted: 1 February, 2021
African swine fever virus factory showing virus particles forming in red.

Developing effective vaccines and treatments against African swine fever virus (ASFV), which kills up to 100 percent of the pigs it infects, has been difficult owing to the virus’s large genome and lack of understanding about how it replicates within cells. Recent bioimaging studies from The Pirbright Institute have uncovered how ASFV forms new copies of itself in areas called viral factories, information which could inform future antiviral treatment development.

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