In a new discovery, scientists from The Pirbright Institute confirm that cholesterol production and transport play a crucial role in how Marek’s disease virus (MDV) infects poultry cells. Researchers also found that inhibiting a protein involved in this pathway can reduce virus replication and spread between cells. These results pave the way for the design of new antivirals and vaccines that interrupt the cholesterol pathway to prevent shedding and transmission of the virus among birds.
News from October 2020
The Pirbright Institute will undertake two projects with ECO Animal Health Group plc (ECO) to develop vaccine candidates for porcine respiratory and reproductive syndrome virus (PRRSV). The first project is a tripartite collaboration between The Pirbright Institute, The Vaccine Group (TVG) and ECO whilst the second project is a joint collaboration between Pirbright and ECO.