Dr Mark Fife and his team are investigating how the genes of host animals and viruses change during infection. This helps them to understand which genes are involved in defending the host from viral attack, which they can use to inform vaccine development.
Scientists at The Pirbright Institute have demonstrated that production and storage of fat is required for Marek’s disease virus (MDV) replication in chickens. Their research identifies new pathways that are involved in the development of the disease which can help generate control strategies to reduce virus spread.
After more than two years preparation Dr Nick Lyons and Dr Georgina Limon-Vega from The Pirbright Institute commenced a Crimean-Congo haemorrhagic fever (CCHF) vaccine trial in Bulgaria on 5 March 2019. If successful, this could pave the way for the first licensed vaccine that is demonstrated to be effective against this infection.
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