Dr Klaudia Chrzastek
Klaudia graduated as a Veterinary Surgeon from Wroclaw University of Environmental and Life Science, Poland. She then started her PhD focused on the effects of ODN CpG motifs and LPS on immune responses, particularly those of the innate immune response driven by chicken Toll-like receptors. She finished her PhD in 2015, obtaining PhD degree in Veterinary Medicine specializing in avian immunology. She also undertook a national veterinary specialisation in Diseases of birds, and became a title of Veterinary specialist in 2012.
In 2013, she joined the Avian Immunology Group at The Roslin Institute, and continued to work on ODN CpG motif recognition by chicken TLR21 receptor. Afterwards, Klaudia started her traineeship at European Food and Safety Authority (EFSA), Risk Assessment and Scientific Assistance Department (Italy) and gained experience in Food and Safety.
In 2015, she started her postdoctoral appointment at the United States Department of Agriculture (USDA), Agricultural Research Service (ARS), US National Poultry Research Center. She worked with North American H5 and H7 HPAIV isolates under BSL3+ and ABSL3+ containment. The work included vaccine efficiency studies, pathogenesis and transmission research in poultry species. She also explored the use of primer free unbiased deep sequencing of viral genomes using random primed cDNA synthesis and reverse genetic approaches.
In July 2018, Klaudia joined Dr. Holly Shelton’s Influenza Viruses Group at Pirbright to carry out the research about influenza virus transmission dynamics in avian population, including host/pathogen interaction. The recent study aims to characterize the interaction between host microbiota and H9N2 influenza virus infection. This involves the use of whole genome and metagenomic shotgun sequencing methods.