Dr Ismar Haga

Real name:

Postdoctoral Scientist

Cell Biology, Innate Immunity, Virology

Ismar studied for his BSc and MSc degrees at the State University of Campinas (UNICAMP) in Brazil before completing his PhD at Imperial College London. After post-doctoral positions at Trinity College Dublin (Ireland) and the Ludwig Institute for Cancer Research (Brazil), Ismar joined Dr Pip Beard’s group at the Roslin Institute, University of Edinburgh in 2011 before moving to The Pirbright Institute in 2016.

Ismar’s main research interests are poxvirology and innate immunity, with special focus on virus/host interactions. Some of his previous works include the characterisation of two Vaccinia virus proteins that inhibit IL-1/TLR signalling and the discovery of a novel function for TRAF2 in Vaccinia virus entry. At Pirbright, Ismar is continuing to research how poxviruses (both orthopoxviruses and capripoxviruses) interact with their hosts.

News
Publications

Landmark study by Pirbright uncovers crucial details of lumpy skin disease virus transmission by insects

Haga I R, Martins S S, Hosomi S T, Vicentini F, Tanaka H, Gatti M S V (1999)

Identification of a bisegmented double-stranded RNA Virus (Picobirnavirus) in faeces of giant anteaters (Myrmecophaga tridactyla)

Veterinary Journal 158 (3) , 234-236

Publisher’s version: https://doi.org/10.1053/tvjl.1999.0369

Harte M T, Haga I R, Maloney G, Gray P, Reading P C, Bartlett N W, Smith G L, Bowie A, O'Neill L A J (2003)

The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense

Journal of Experimental Medicine 197 (3) , 343-351

Publisher’s version: http://dx.doi.org/10.1084/jem.20021652

Marshall-Clarke S, Downes J E, Haga I R, Bowie A G, Borrow P, Pennock J L, Grencis R K, Rothwell P (2007)

Polyinosinic acid is a ligand for Toll-like receptor 3

Journal of Biological Chemistry 282 (34) , 24759-24766

Publisher’s version: http://www.jbc.org/content/282/34/24759.abstract

Oliveira L B, Haga I R, Villa L L (2018)

Human papillomavirus (HPV) 16 E6 oncoprotein targets the Toll-like receptor pathway

Journal of General Virology 99 (5) , 667-675

Publisher’s version: https://dx.doi.org/10.1099/jgv.0.001057

Stack J, Haga I R, Schröder M, Bartlett N W, Maloney G, Reading P C, Fitzgerald K A, Smith G L, Bowie A G (2005)

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence

Journal of Experimental Medicine 201 (6) , 1007-1018

Publisher’s version: http://dx.doi.org/10.1084/jem.20041442

Almine J F, O'Hare C A, Dunphy G, Haga I R, Naik R J, Atrih A, Connolly D J, Taylor J, Kelsall I R, Bowie A G, Beard P M, Unterholzner L (2017)

IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

Nature Communications 8 , 14392

Publisher’s version: http://dx.doi.org/10.1038/ncomms14392

Groups

Large DNA Viruses

Dr Ismar Haga

Landmark study by Pirbright uncovers crucial details of lumpy skin disease virus transmission by insects

Identification of a bisegmented double-stranded RNA Virus (Picobirnavirus) in faeces of giant anteaters (Myrmecophaga tridactyla)

The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense

Polyinosinic acid is a ligand for Toll-like receptor 3

Human papillomavirus (HPV) 16 E6 oncoprotein targets the Toll-like receptor pathway

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence

IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

Pages

Trim content

You are here

Groups

Dr Ismar Haga

Pages

Trim content