Dr Andrew Broadbent

Real name:

Honorary Fellow

Immunology, Vaccinology, Virology

Dr Andrew Broadbent led the birnaviruses group at Pirbright that conducted research into the pathogenesis and control of avian immunosuppressive viruses that can exacerbate the spread of zoonotic diseases. He holds a degree in Veterinary Medicine from the University of Cambridge, a Masters degree from the London School of Hygiene and Tropical Medicine (LSHTM), and a PhD in Microbiology and Immunology from Imperial College London. Prior to joining Pirbright, Andrew was a Postdoctoral Fellow at the National Institutes of Health (NIH) in the US.

News
Publications

Reddy VRAP, Nazki S, Asfor A, Broadbent AJ (2023)

An Infectious Bursal Disease Virus (IBDV) Reverse Genetics Rescue System and Neutralization Assay in Chicken B Cells

Current Protocols 3 (1) , e639

Publisher’s version: https://doi.org/10.1002/cpz1.639

Dulwich K L, Asfor A, Gray A, Giotis E S, Skinner M A, Broadbent A J (2020)

The stronger downregulation of in vitro and in vivo innate antiviral responses by a very virulent strain of infectious bursal disease virus (IBDV), compared to a classical strain, is mediated, in part, by the VP4 protein

Frontiers in Cellular and Infection Microbiology 10 , 315

Publisher’s version: https://doi.org/10.3389/fcimb.2020.00315

Campbell E A, Reddy V R A P, Gray A G, Wells J, Simpson J, Skinner M A, Hawes P C, Broadbent A J (2020)

Discrete virus factories form in the cytoplasm of cells co-infected with two replication competent tagged reporter birnaviruses, that subsequently coalesce over time

Journal of Virology 94 (13) , e02107-19

Publisher’s version: https://doi.org/10.1128/JVI.02107-19

Dulwich K L, Asfor A S, Gray A G, Venugopal N, Broadbent A J (2018)

An ex vivo chicken primary bursal-cell culture model to study infectious bursal disease virus pathogenesis

Journal of Visualized Experiments 140 , e58489

Publisher’s version: https://doi.org/10.3791/58489

Sadigh Y, Powers C, Spiro S, Pedrera M, Broadbent A, Nair V (2018)

Gallid herpesvirus 3 SB-1 strain as a recombinant viral vector for poultry vaccination

npj Vaccines 3 (1) , 21

Publisher’s version: https://dx.doi.org/10.1038/s41541-018-0056-6

Dr Andrew Broadbent

IBDV protein that dampens poultry immune response could inform vaccine development

Pirbright scientists show how infectious bursal disease viruses may swap genetic material during infection

Science Spotlight: Dr Andrew Broadbent

Pirbright innovation recognised at the BBSRC Innovator of the Year Awards

Pirbright scientists produce lab technique which reduces need for experimental chickens

Genetic diversity, recombination and cross-species transmission of a waterbird gammacoronavirus in the wild

An Infectious Bursal Disease Virus (IBDV) Reverse Genetics Rescue System and Neutralization Assay in Chicken B Cells

The stronger downregulation of in vitro and in vivo innate antiviral responses by a very virulent strain of infectious bursal disease virus (IBDV), compared to a classical strain, is mediated, in part, by the VP4 protein

Discrete virus factories form in the cytoplasm of cells co-infected with two replication competent tagged reporter birnaviruses, that subsequently coalesce over time

An ex vivo chicken primary bursal-cell culture model to study infectious bursal disease virus pathogenesis

Gallid herpesvirus 3 SB-1 strain as a recombinant viral vector for poultry vaccination

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Dr Andrew Broadbent

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