Prof Bryan Charleston

Real name:

Director

Immunology, Veterinary Practitioner, Virology

Prof Bryan Charleston obtained a BVetMed from the Royal Veterinary College, University of London, UK in 1982. After a period of time in Large Animal Practice, he studied for a Masters degree in Molecular Biology at University College London in 1988, then a PhD degree, as a Wellcome Trust Scholar, from the University of London, UK, in 1991. He then carried out postdoctoral research, as a Wellcome Trust Post-doctoral fellow, at the Royal Veterinary College and the Babraham Institute, Cambridge for three years.

He joined The Pirbright Institute in 1994 and focused on studies of the immune response to viral infections in cattle. In addition, he provided advice and expertise on the design of infectious disease challenge models for a wide range of pathogens in important agricultural species. His research is focused on understanding the immune response to foot-and–mouth disease virus (FMDV) in cattle to develop novel vaccines.

News
Publications

Pirbright strengthens animal disease partnership with India

Veterinary Vaccine Centre welcomed in White Paper

Pirbright and VIDO expands collaboration to advance vaccine manufacturing

Professor Bryan Charleston elected as Fellow of the Royal Society

Pirbright showcases the best in science and community with open-door event

Loureiro S, Porta C, Maity H, Perez E, Bagno F, Kotecha A, Fry E, Ren J, Stuart D, Hoenemann H, Serrano A, van den Born E, Charleston B, Jones I (2018)

Universal detection of foot and mouth disease virus based on the conserved VP0 protein

Wellcome Open Research 3 , 88

Publisher’s version: https://dx.doi.org/10.12688/wellcomeopenres.14655.1

Tungatt K, Dolton G, Morgan S B, Attaf M, Fuller A, Whalley T, Hemmink J D, Porter E, Szomolay B, Montoya M, Hammond J A, Miles J J, Cole D K, Townsend A, Bailey M, Rizkallah P J, Charleston B, Tchilian E, Sewell A K (2018)

Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig

PLoS Pathogens 14 (5) , e1007017

Publisher’s version: https://doi.org/10.1371/journal.ppat.1007017

Holzer B, Morgan S B, Matsuoka Y, Edmans M, Salguero F J, Everett H, Brookes S M, Porter E, MacLoughlin R, Charleston B, Subbarao K, Townsend A, Tchilian E (2018)

Comparison of heterosubtypic protection in ferrets and pigs induced by a single cycle influenza vaccine

Journal of Immunology 200 (12) , 4068-4077

Publisher’s version: https://doi.org/10.4049/jimmunol.1800142

Morgan S B, Holzer B, Hemmink J D, Salguero F J, Schwartz J C, Agatic G, Cameroni E, Guarino B, Porter E, Rijal P, Townsend A, Charleston B, Corti D, Tchilian E (2018)